CHICAGO, IL. -- Harold Ramis, whose acting credits included Ghostbusters and Stripes, died early Monday from complications of autoimmune inflammatory vasculitis, his wife Erica Mann Ramis told the Chicago Tribune. He was 69.

Ramis was also known for his writing and directing work on blockbusters Caddyshack and Groundhog Day. Other comedy credits include National Lampoon's Animal House, National Lampoon's Vacation and Analyze This.

Ramis was born in Chicago and moved his family to the North Shore area in the '90s.

According to the Tribune, he underwent surgery for diverticulitis in 2010. He suffered complications and spent time at the Mayo Clinic and Rehabilitation Institute of Chicago. Ramis relapsed less than two years later, the Tribune reports, and never fully recovered.

Ramis got his start as head writer and actor for the TV series Second City Television (SCTV) and a writer for Animal House. He pursued a film career that led to directing, writing and starring in dozens of movies that many consider classics.

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